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Contraindicated (one)pentobarbital decreases amounts of vandetanib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Avoid coadministration with powerful CYP3A4 inducers; these medication cut down publicity to vandetanib by as much as forty%.Pentobarbital also is effective by inhibiting glutamate, which happens to be respon

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